أ.د. هانى احمد مصطفى محمد عمر المنصب الأكاديمي: أستاذ الأدوية والسموم مناصب أخري: 1- Vice-Dean, College of Pharmacy, University of Sharjah 2- Head of Department , College of Pharmacy, University of Sharjah الأتصال: hany.omar@pharm.bsu.edu.eg الدرجات العلمية: ٢٠١٠ دكتوراة في الأدوية والسموم جامعة ولاية أوهايو الولايات المتحدة الأمريكية ٢٠٠٥ ماجيستير في الأدوية والسموم كلية الصيدلة جامعة القاهرة مصر ١٩٩٨ بكالوريوس في العلوم الصيدلية كلية الصيدلة جامعة القاهرة مصر عنوان رسالة الماجستير: Pharmacological study of the possible interactions between certain analgesics and some antioxidants in experimental animals عنوان رسالة الدكتوراه: دراسات فارماكولجى جزيئية ودراسات ما قبل السريرية لعوامل جزيئية صغيرة جديدة مستهدفة علاج سرطان الخلايا الكبدية Molecular Pharmacology and Preclinical Studies of Novel Small-Molecule Targeted agents for the Treatment of Hepatocellular Carcinoma المهام التدريسية: Pharmacology and Toxicology أبحاث مختارة: 1- MA. Abdelgawad, SNA Bukhari, A Musa, M Elmowafy, MH Elkomy, AA Nayl, AH El-Ghorab, Ibrahim H Alsohaimi, MS Abdel-Bakky, IO Althobaiti, HA Altaleb, Hany A. Omar, AH Abdelazeem, MA Zaki, ME Shaker, HAH Elshemy. New Sulphamethoxazole Derivatives As Selective Carbonic Anhydrase IX And XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modelling. Pharmaceuticals. (Accepted) 2- Amany A. Azouz, Hany A. Omar, Fatema Hersi, Fares E. M. Ali, Asmaa Mohammed M. Hussein Elkelawy. Renoprotective effect of vinpocetine against ischemia/reperfusion injury: modulation of NADPH oxidase/Nrf2, IKKβ/NF-κB p65, and cleaved caspase-3 expressions. Journal of Biochemical and Molecular Toxicology https://doi.org/10.1002/jbt.23046 (Accepted) 3- Anbar HS, Shehab NG, El-Rouby NMM, Ansari MA, Chenoth H, Majeed M, Naeem K, Hersi F, Omar HA. Upadacitinib protects against cisplatin-induced renal and hepatic dysfunction without impairing its anticancer activity. European Journal of Pharmaceutical Sciences, 2022 Feb 18:106149. https://doi.org/10.1016/j.ejps.2022.106149 . 4- Mohamad Hamad, Farah Al-Marzooq, Vunnam Srinivasulu, Hany A. Omar, Ashna Sulaiman, Dana M. Zaher, Gorka Orive and Taleb H. Al-Tel. Antibacterial Activity of Small Q14 Molecules Which Eradicate Methicillin-Resistant Staphylococcus aureus Persisters. Frontiers in Microbiology, 2022 Feb 1;13:823394. https://doi.org/10.3389/fmicb.2022.823394 5- Amany A. Azouz, Hany A. Omar, Fatema Hersi, Fares E. M. Ali, Asmaa Mohammed M. Hussein Elkelawy. Impact of the ACE2 activator xanthenone on tacrolimus nephrotoxicity: Modulation of uric acid/ERK/p38 MAPK and Nrf2/SOD3/GCLC signaling pathways. Life Sciences, 2022, Jan 1; 288: 120154. https://doi.org/10.1016/j.lfs.2021.120154 6- Ola D. A. Shammout, Naglaa S. Ashmawy, Sarra B. Shakartalla, Alaa M. Altaie, Mohammad H. Semreen, Hany A. Omar, Sameh S. M. Soliman. Comparative sphingolipidomic analysis reveals significant differences between doxorubicin-sensitive and -resistance MCF-7 cells. PloS ONE, 2021 Oct 12;16(10):e0258363 https://doi.org/10.1371/journal.pone.0258363 7- Dana M. Zaher, Iman M.Talaat, Amal Hussein, Mahmood Y.Hachim, Hany A. Omar*. Differential expression of pyruvate dehydrogenase E1A and its inactive phosphorylated form among breast cancer subtypes. Life Sciences, 2021, Nov 1; 284: 119885 https://doi.org/10.1016/j.lfs.2021.119885 8- A. Manandhar, V. Srinivasulu, M. Hamad, H. Tarazi, Hany A. Omar, Dennis J. Colussi, J. Gordon, W. Childers, Michael L. Klein, Taleb H. Al-Tel, Magid Abou-Gharbia, and Khaled M. Elokely. Discovery of Novel Small-Molecule Inhibitors of SARS-CoV-2 Main Protease as Potential Leads for COVID-19 Treatment. Journal of Chemical Information and Modeling, 2021, Sep 27;61(9):4745-4757 https://doi.org/10.1021/acs.jcim.1c00684 9- Shifaa M. Abdina, Mai F. Tolba, Dana M. Zaher, Hany A. Omar*. Nuclear factor-κB signaling inhibitors revert multidrug-resistance in breast cancer cells Chemico-Biological Interactions, 2021 May 1: 340: 109450; https://doi.org/10.1016/j.cbi.2021.109450 10- Dana MZ, Wafaa S. Ramadan, Raafat El-Awady, Hany A. Omar, Fatema Hersi, Vunnam Srinivasulu, Ibrahim YH, Farah Al -Marzooq, Cijo GV, Salim Merali, Carmen Merali, Nelson C. Soares, Paul Schilf, Saleh M. Ibrahim, Taleb H. Al-Tel. A Novel benzopyrane derivative targeting cancer cell metabolic and survival pathways. 2021 Cancers 2021, 13, 2840 https://doi.org/10.3390/cancers13112840 11- Noura Khaiwa, Noor R. Maarouf, Mhd H. Darwish, Dima W.M. Alhamad, Anusha Sebastian, Mohamad Hamad, Hany A. Omar, GorkaOrive, Taleb H.Al-Tel Camptothecin's Journey from Discovery to WHO Essential Medicine: Fifty Years of Promise. European Journal of Medicinal Chemistry, 2021, Nov 5;223: 113639 https://doi.org/10.1016/j.ejmech.2021.113639 12- Gaber Ali, Hany Omar*, Fatema Hersi, Amira Abo-Youssef, Osama Ahmed and Wafaa Mohamed. The Protective Role of Etoricoxib Against Diethylnitrosamine/2-acetylaminofluorene-induced Hepatocarcinogenesis in Wistar Rats: The Impact of NF-κB/COX-2/PGE2 Signaling. Current Molecular Pharmacology. 2021, Jul 7. https://doi.org/10.2174/1874467214666210708103752 13- Khuloud Bajbouj, Rakhee Ramakrishnan, Maha Saber-Ayad, Hany A. Omar, Narjes Sharif-Askari, Jasmin Shafarin, Adel Elmoselhi, Ahmed Ihmaid, Suhib Al Haj Ali, Abdulla Alalool, Reem Abdullah, Qutayba Hamid. PRMT5 Selective Inhibitor Enhances Therapeutic Efficacy of Cisplatin in Lung Cancer Cells. International Journal of Molecular Sciences, 2021, 22, 6131. https://doi.org/10.3390/ijms22116131 14- Jui-Hsiang Hung, Han-Yi Cheng, Yung-Chieh Tsai; Hsien-An Pan; Hany A. Omar, Chien-Chih Chiu; Yin-Mei Su; Yung-Ming Lin, Yen-Ni Teng. LRWD1 expression is regulated through DNA methylation in human testicular embryonal carcinoma cells. Basic and Clinical Andrology, 2021 May 20;31(1):12 https://doi.org/10.1186/s12610-021-00130-y 15- Leen M Eldohaji, Bahgat Fayed, Alshaimaa M Hamoda, Mai Ershaid, Shifaa Abdin, Tasneem B Alhamidi, Mohammad G Mohammad, Hany A. Omar, Sameh S M Soliman. Potential targeting of Hep3B liver cancer cells by lupeol isolated from Avicennia marina. Arch Pharm (Weinheim) . 2021 Jun 4;e2100120. https://doi.org/10.1002/ardp.202100120 16- Shaden A. M. Khalifa, Mohamed H. Elashal, Nermeen Yosri, Ming Du, Syed G. Musharraf, Lutfun Nahar, Satyajit D. Sarker, Zhiming Guo,Wei Cao, Xiaobo Zou, Aida A. Abd El-Wahed, Jianbo Xiao, Hany A. Omar, Mohamed-Elamir F. Hegazy and Hesham R. El-Seedi. Bee Pollen: Current Status and Therapeutic Potential. Nutrients 2021, 13(6), 1876; https://doi.org/10.3390/nu13061876 17- Samir A. Salama, and Hany A. Omar. Modulating NF-κB, MAPK, and PI3K/AKT signaling by ergothioneine attenuates iron overload-induced hepatocellular injury in rats. Journal of Biochemical and Molecular Toxicology 2021 Feb 13:e22729; https://doi.org/10.1002/jbt.22729 18- Bushra Mdkhana, Dana M. Zaher, Shifaa M. Abdin, and Hany A. Omar*. Tangeretin boosts the anticancer activity of metformin in breast cancer cells via curbing the energy production. Phytomedicine 2021, Jan; 83: 153470. https://doi.org/10.1016/j.phymed.2021.153470 19- Dima W. Alhamad, Sara M. Elgendy, Taleb H. Altel, Hany A. Omar*. Tangeretin as an adjuvant and chemotherapeutic sensitizer against various types of cancers, a comparative overview. Journal of Pharmacy and Pharmacology 2021, Mar 27;73(5):601-610 https://doi.org/10.1093/jpp/rgab013 20- Shatha K. Alyammahi, Shifaa M. Abdin, Dima W. Alhamad, Sara M. Elgendy, Amani T. Altell, Hany A. Omar*. The dynamic association between COVID-19 and chronic disorders: An updated insight into prevalence mechanism and therapeutic modalitie. Infection, Genetics and Evolution 2021, Jan; 87: 104647. https://doi.org/10.1016/j.meegid.2020.104647 21- RM Sbenati , SO Zaraei, MI El-Gamal, HS Anbar, H Tarazi, MM Zoghbor, NA Mohamood, MM Khakpour, DM Zaher, Hany A. Omar, NN Alach, MK Shehata, and R El-Gamal. Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells. European Journal of Medicinal Chemistry 2021, Jan 15;210: 113081. https://doi.org/10.1016/j.ejmech.2020.113081 22- Schilf P, Srinivasulu V, Bolognesi ML, Ibrahim S, Majdalawieh A, Abu-Yousef IA, Omar, HA, ElAwady R, Al-Tel TH. Design and synthesis of nature-inspired, chromenopyrroles as potential modulators of mitochondrial metabolism. Medicinal Chemistry Research, 2021, Nov 30, 635–646 https://doi.org/10.1007/s00044-020-02669-3 23- PS Chen , HP Hsu , NN Phan , MC Yen , FW Chen , YW Liu , FP Lin , SY Feng , TL Cheng , PH Yeh, Hany A. Omar , Z Sun , J Jiang , YS Chan , MD Lai , JH Hung. CCDC167 as a potential therapeutic target and regulator of cell cycle-related networks in breast cancer. Aging 2020; doi.org/10.18632/aging.202382 https://doi.org/10.18632/aging.202382 24- Soliman S, Alhamidi T, Abdin S, Almehdi A, Semreen M, Alhumaidi R, Shakartalla S, Haider M, Husseiny M, Omar H. Effective targeting of breast cancer cells (MCF7) via novel biogenic synthesis of gold nanoparticles using cancer-derived metabolites. PloS ONE, 2020 Oct 6;15(10):e0240156 https://doi.org/10.1371/journal.pone.0240156 25- Sara M. Elgendy, Shatha K. Alyammahi, Dima W. Alhamad, Shifaa M. Abdin, Hany A. Omar*. Ferroptosis: An emerging approach for targeting cancer stem cells and drug resistance. Critical Reviews in Oncology/Hematology, 2020, Nov; 155: 103095 https://doi.org/10.1016/j.critrevonc.2020.103095 26- Shifaa M. Abdina, Sara M. Elgendy, Shatha K. Alyammahi, Dima W. Alhamad, Hany A. Omar*. Tackling the cytokine storm in COVID-19, challenges, and hopes. Life Sciences, 2020, Jul 11;257:118054 https://doi.org/10.1016/j.lfs.2020.118054 27- El-Shaimaa A. Arafa, Wafaa R. Mohamed, Dana M. Zaher, Hany A. Omar*. Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways. Toxicology and Applied Pharmacology, 2020, Feb, 391, 114919 https://doi.org/10.1016/j.taap.2020.114919 28- Fatema Hersi, Hany A. Omar*, Raed A. Al-Qawasmeh, Zainab Ahmad, Areej M. Jaber, Dana M. Zaher, Taleb H. Al-Tel. Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins. Scientific Reports, 2020, Feb 19;10(1):2893. https://doi.org/10.1038/s41598-020-59685-x 29- Ahmed H. Abdelazeem, Alaa M. Alqahtani, Hany A. Omar, Syed Nasir Abbas Bukhari, Ahmed M.Gouda. Synthesis, biological evaluation and kinase profiling of novel S-benzo[4,5]thiazolo[2,3-c][1,2,4]triazole derivatives as cytotoxic agents with apoptosis-inducing activity. Journal of Molecular Structure, 2020, Nov, 1219, 128567 https://doi.org/10.1016/j.molstruc.2020.128567 30- Shahira El-Menshawe, Heba Abou Taleb, Mina Saweris, Dana Zaher, Hany A. Omar*. The Use of New Quinazolinone Derivative and Doxorubicin Loaded Solid Lipid Nanoparticles: An Investigation into the Influence of Lipids and Surfactant in Controlling the Criteria of Developed Vesicles and Reversal of Drug Resistance. Journal of Drug Delivery Science and Technology, 2020, Feb, 56; 101569. https://doi.org/10.1016/j.jddst.2020.101569 31- Dana M. Zaher, Mohammed I. El-Gamal, Hany A. Omar *, Sarah N. Aljareh , Salma A. Al-Shamma, Aya J. Ali, Sumera Zaib, and Jamshed Iqbal, Recent advances of alkaline phosphatase isoenzymes and their inhibitors. Archiv der Pharmazie, 2020 https://doi.org/10.1002/ardp.202000011 . 32- Mohammed I.El-Gamal, Hany A. Omar*, Mohammad H. Semreen, Israa A.Younes, Youmna Y.Zaghloul, Ayat E.Abbas, Iman G.Moussa, Fatima Hersi, Chang-Hyun Ohe, Antiproliferative activity of cycloalkanecarboxamide derivatives possessing sulfonate or sulfamate moiety. Bioorganic Chemistry, February 2020, 97; 103677. https://doi.org/10.1016/j.bioorg.2020.103677 33- Nour Moussa-Pacha, Shifaa Abdin, Hany A. Omar, Hasan Alniss, Taleb H. Al-Tel. BACE1 Inhibitors: Current status and future directions in treating Alzheimer's disease. Medicinal Research Reviews, 2020, Jan;40(1):339-384. https://doi.org/10.1002/med.21622 34- Srinivasulu, V; Khanfar, A.; Omar, Hany; ElAwady, R; Sieburth, S; Sebastian, A; Zaher, D; Al Marzooq, F; Hersi, F; Al-Tel, T. Sequencing [4+1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs. Journal of Organic Chemistry 2019 Nov 15;84(22):14476-14486 https://doi.org/10.1021/acs.joc.9b01919 35- Hany A. Omar*, Ahmed T. El-Serafi, Fatema Hersi, El-Shaimaa A. Arafa, Dana M. Zaher, Mohamed Madkour, Hany H. Arab and Mai F. Tolba. Immune-Modulatory MicroRNAs and Cancer Immune Evasion. The FEBS Journal, 2019, Jul 15. ; 286 (18): 3540–3557 https://doi.org/10.1111/febs.15000 36- El-Gamal MI, Ullah S, Zaraei SO, Jalil S, Zaib S, Zaher DM, Omar HA, Anbar HS, Pelletier J, Sévigny J, Iqbal J. Biological evaluation and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase. European Journal of Medicinal Chemistry, 2019, Nov 1;181:111560 https://doi.org/10.1016/j.ejmech.2019.07.063 37- Khaled R.A. Abdellatif, Wael A.A. Fadaly, Yaser A. Mostafa, Dana M. Zaher, Hany A.Omar. Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities. Bioorganic Chemistry, 2019, Jul 19;91:103132 https://doi.org/10.1016/j.bioorg.2019.103132 38- Mai F. Tolba, Hany A. Omar*, Fatima Hersi, Ane C. F. Nunes, Ayman M. Noreddin. The impact of Catechol-O-methyl transferase knockdown on the cell proliferation of hormone-responsive cancers. Molecular and Cellular Endocrinology, 2019 May; 488: 79-88 https://doi.org/10.1016/j.mce.2019.03.007 39- Hany A. Omar*, Mai F. Tolba. Tackling molecular targets beyond PD-1/PD-L1: Novel approaches to boost patients' response to cancer immunotherapy. Critical Reviews in Oncology/Hematology, 2019, Mar;135:21-92 https://doi.org/10.1016/j.critrevonc.2019.01.009 40- Pao-Lin Kuo, Jie-Yun Tseng, Hau-Ing Chen, Chia-Yun Wu, Hany A Omar, Chia-Yih Wang, Han-Yi Cheng, Chao-Chin Hsu, Tzu-Fun Fu, Yen Ni Teng. Identification of SEPTIN12 as a novel target of the androgen and estrogen receptors in human testicular cells. Biochimie, 2019 Mar;158:1-9 https://doi.org/10.1016/j.biochi.2018.11.018 41- Srinivasulu V, Schilf P, Ibrahim S, Khanfar MA, Sieburth SM, Omar Hany, Sebastian A, AlQawasmeh RA, O'Connor MJ, Al-Tel TH. Multidirectional Desymmetrization of Pluripotent Building Block en Route to Diastereoselective Synthesis of Complex Nature-Inspired Scaffolds. Nature Communication 2018, Nov 26;9(1):4989. https://doi.org/10.1038/s41467-018-07521-2 42- Wei-De Wu, Pin-Shern Chen, Hany A. Omar, El-Shaimaa Arafa, Hung-Wei, Pan, Jing-Yueh Jeng, Jui-Hsiang Hung. Antrodia cinnamomea boosts the anti-tumor activity of sorafenib in xenograft models of human hepatocellular carcinoma. Scientific Reports 2018, Aug 27;8(1):12914 https://doi.org/10.1038/s41598-018-31209-8 43- Rasha M. Hussein, Wafaa R. Mohamed, Hany A. Omar. A neuroprotective role of kaempferol against chlorpyrifos-induced oxidative stress and memory deficits in rats via GSK3β-Nrf2 signaling pathway. Pesticide Biochemistry and Physiology 2018 Nov;152:29-37 https://doi.org/10.1016/j.pestbp.2018.08.008 44- San-Yuan Chen, Ying-Ray Lee, Ming-Chia Hsieh, Hany A. Omar, Yen-Ni Teng, Ching-Yen Lin, Jui-Hsiang Hung. Enhancing the anticancer activity of Antrodia cinnamomea in hepatocellular carcinoma. Frontiers in Pharmacology 2018 Jul; 9: 780 https://doi.org/10.3389/fphar.2018.00780 45- Hany A. Omar* and Mai F. Tolba. Caffeic acid phenethyl ester guards against benign prostate hypertrophy in rats: Role of IGF-1R/ Protein Kinase-B (Akt)/ β-catenin signaling. IUBMB Life 2018 Mar; 70(6):519-528 https://doi.org/10.1002/iub.1743 46- J.H. Hung, S.K Wee, H.A. Omar, C.H Su, P.S. Chen, C.C. Chiu, M.S. Wu, Y.N. Teng. Nuclear factor erythroid-2-related factor regulates LRWD1 expression and cellular adaptation to oxidative stress in human embryonal carcinoma cells. Biochimie, 2018 May;148:99-106 https://doi.org/10.1016/j.biochi.2018.03.001 47- S.A. Abdelatef, M.T. El-Saadi, N.H. Amin, A.H. Abdelazeem, Hany A. Omar, K.R.A. Abdellatif. Design, Synthesis and Anticancer Evaluation of Novel Spirobenzo[h]chromene and Spirochromane Derivatives with Dual EGFR and B-RAF Inhibitory activities. European Journal of Medicinal Chemistry, 2018 May;150:567-578 https://doi.org/10.1016/j.ejmech.2018.03.001 48- Salama SA, Arab HH, Omar HA, Gad HS, Abd-Allah GM, Maghrabi IA, Al Robaian MM. L-carnitine mitigates UVA-induced skin tissue injury in rats through downregulation of oxidative stress, p38/c-Fos signaling, and the proinflammatory cytokines. Chemico-Biological Interactions, 2018, Apr;285:40-47 https://doi.org/10.1016/j.cbi.2018.02.034 49- Soliman S, Mohammad MG, El-Keblawy AA, Omar HA, Abouleish M, Madkour M, Elnaggar A, Hosni RM. Mechanical and phytochemical protection mechanisms of Calligonum comosum in arid deserts. PloS ONE, 2018 Feb 7;13(2): e0192576. https://doi.org/10.1371/journal.pone.0192576 50- Shifaa M. Abdin, Dana M. Zaher, El-Shaimaa A. Arafa and Hany A. Omar*. Tackling the cancer resistance by immunotherapy: Updated clinical impact and safety of PD-1/PD-L1 inhibitors. Cancers, 2018, Jan 10(2), 32; https://doi.org/10.3390/cancers10020032 51- Mai F. Tolba and Hany A. Omar*, Immunotherapy, an evolving approach for the management of triple negative breast cancer: converting non-responders to responders. Critical Reviews in Oncology/Hematology, 2018, Feb;122:202-207 https://doi.org/10.1016/j.critrevonc.2018.01.005 52- Abdel-Nasser El-Shorbagi, Mohamed El-Naggar, Hamadeh Tarazi, Sachin Chaudhary, Hajjaj Abdu-Allah, Fatema Hersi, Hany A. Omar. Bis-(5-substituted-2-thiono-1,3,5-thiadiazinan-3-yl) butane as a scaffold of anti-proliferative activity, blended by a multicomponent process. Medicinal Chemistry Research, 2018, Apr;27: 1103–1110 https://doi.org/10.1016/S0223-5234(97)89645-6 53- Hany A. Omar*, Dana M. Zaher, Vunnam Srinivasulu, Fatema Hersi, Hamadeh Tarazi, Taleb H. Al-Tel. Design, synthesis and biological evaluation of new pyrrolidine carboxamide analogues as potential chemotherapeutic agents for hepatocellular carcinoma. European Journal of Medicinal Chemistry, 2017 Oct 20; 139:804-814. https://doi.org/10.1016/j.ejmech.2017.08.054 54- Ahmed M. Gouda, Ahmed H. Abdelazeem, Hany A. Omar, Ashraf N. Abdalla, Mohammed A.S. Abourehab, Hamed I. Ali. Pyrrolizines: design, synthesis, anticancer evaluation and investigation of the potential mechanism of action. Bioorganic & Medicinal Chemistry 2017 Oct 15;25(20):5637-5651 https://doi.org/10.1016/j.bmc.2017.08.039 55- Hany H. Arab, Samir A. Salama, Tamer M. Abdelghany, Hany A. Omar, El-Shaimaa A. Arafa, El- Ibrahim A. Maghrabi. Camel milk attenuates rheumatoid arthritis via inhibition of mitogen activated protein kinase pathway. Cellular Physiology and Biochemistry, 2017 Sep 20;43(2):540-552. https://doi.org/10.1159/000480527 روابط أخري: Linkedin Google Scholar Scopus السيرة الذاتية