المواقع الشخصيه لاعضاء هيئة التدريس

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أحمد حسن أمين عبدالعظيم

استاذ مساعد

المواد الدراسيه

الكيمياء الصيدلية

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المؤلفات

4/12/2016

لا يوجد

الأبحاث

1. S. M. El-Moghazy Aly, D. E. Abdel Rahman, S. E. Abbas, M. A. Mohammed and A. H. Amin Abdelazeem. Design and synthesis of some substituted acridine derivatives of anticipated antitumor activity. Bull. Pharm. Sci., Assiut University, 2007, 30, 213-234.

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2. Michael J. Seminerio; Matthew J. Robson; Ahmed H. Abdelazeem; Christophe Mesangeau; Seshulatha Jamalapuram; Bonnie A. Avery; Christopher R. McCurdy; Rae R. Matsumoto. Synthesis and Pharmacological Characterization of a Novel Sigma Receptor Ligand with Improved Metabolic Stability and Antagonistic Effects against Methamphetamine. The AAPS Journal, 2011, 14, 43-51. (Impact Factor = 5.7)

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3. Seshulatha Jamalapuram, Pradeep Kumar Vuppala, Ahmed H. Abdelazeem, Christopher R. McCurdy and Bonnie A. Avery. Ultra performance liquid chromatography tandem mass spectrometry method for the determination of AZ66, a sigma receptor ligand, in rat plasma and its application to in vivo pharmacokinetics. Biomedical Chromatography, 2013, 27 (8), 1034-1040. (Impact Factor = 2.0)

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4. Ahmed H. Abdelazeem, Shaimaa A. Abdelatef, Mohammed T. El-Saadi, Hany A. Omar, Shabana I. Khan,Christopher R. McCurdy and Samir M. El-Moghazy. Novel Pyrazolopyrimidine Derivatives Targeting COXs and iNOS enzymes; Design, Synthesis and Biological Evaluation as Potential Anti-inflammatory Agents. European Journal of Pharmaceutical Sciences, 2014, 62, 197-211. (Impact Factor = 3.5)

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5. Ahmed H. Abdelazeem, Ahmed M. Gouda, Hany A. Omar, Mai F. Tolba. Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents. Bioorganic Chemistry, 2014, 57, 132–141. (Impact Factor = 2.1)

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6. Ahmed Khames, Ahmed H. Abdelazeem, Maha Habash, and Mutasem O. Taha. Preparation and in vitro characterization of glibenclamide-loaded alginate hexyl-amide beads: a novel drug delivery system to improve the dissolution rate. Pharmaceutical Development and Technology. 2014, 19, 881-890. (Impact Factor = 1.3)

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7. Ahmed M. Gouda, Ahmed H. Abdelazeem, Hany A. Omar. Design, synthesis and pharmacological evaluation of novel pyrrolizine derivatives as potential anticancer agents. Bioorganic Chemistry, 2014, 53, 1-7. (Impact Factor = 2.1)

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8. El-shaimaa A Arafa, Ahmed H Abdelazeem, Hany H Arab and Hany A Omar. OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro. Acta Pharmacologica Sinica, 2014, 35, 394-400. (Impact Factor = 2.6)

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9. Maha Habash, Ahmed H. Abdelazeem, Mutasem O. Taha. Elaborate Ligand-Based Modeling Reveals New Human Neutrophil Elastase Inhibitors. Medicinal Chemistry Research. 2014, 23, 3876-3896. (Impact Factor = 1.7)

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10. Mutasem O. Taha, Maha Habash, Ahmed H. Abdelazeem, Amjad Qandil. Ligand-based modelling Followed by in Vitro Bioassay Yielded New Potent Glucokinase Activators. Journal of Molecular Graphics and Modelling, 2015, 56, 91-102. (Impact Factor = 2.1)

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11. Ahmed H. Abdelazeem, Samir A. Salama, Ibrahim A. Maghrabi. Design, Synthesis and Anti-Inflammatory Evaluation of Novel Diphenylthiazole-Thiazolidinone Hybrids. Archiv Der Pharmazie-Chemistry in Life Sciences, 2015, 348, 518–530. (Impact Factor = 1.5)

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12. Ahmed H. Abdelazeem, Maha Habash, Ibrahim Maghrabi, Mutasem O. Taha, Synthesis and Evaluation of Novel Diphenylthiazole Derivatives as Potential Anti-Inflammatory Agents. Medicinal Chemistry Research. 2015, 24, 3681-3695. (Impact Factor = 1.7)

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13. Ahmed H. Abdelazeem, Shabana I. Khan, Stephen W. White, Kenneth J. Sufka and Christopher R. McCurdy. Design, Synthesis and Biological Evaluation of Bivalent Benzoxazolone and Benzothiazolone Ligands as Potential Anti-inflammatory/Analgesic Agents. Bioorganic & Medicinal Chemistry, 2015, 23, 3248-3259. (Impact Factor = 3.2)

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14. Ahmed H. Abdelazeem, Mohammed T. El-Saadi, Asmaa G. Safi El-Din and Samir M. El-Moghazy. Design, Synthesis and Biological Evaluation of Novel Diphenylthiazole-Thiazolidin-4-one-Based Derivatives as Analgesic/Anti-Inflammatory Agents. Journal of Chemical and Pharmaceutical Research, 2015, 7, 1073-1079. (Impact Factor = 0.4)

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15. Ahmed M. Gouda, Ahmed H. Abdelazeem. An Integrated Overview on Pyrrolizines as Potential Anti-inflammatory, Analgesic and Antipyretic Agents. European Journal of Medicinal Chemistry, 2016, 114, 257-292. (Impact Factor = 3.5)

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16. Ahmed M. Gouda, Hamed I. Ali, Waleed H. Almalki, Mohamed A. Azim, Mohammed A.S. Abourehab, Ahmed H. Abdelazeem. Synthesis, and Biological Evaluation of Some Novel Pyrrolizine Derivatives as COX Inhibitors with Anti-inflammatory/Analgesic Activities and Low Ulcerogenic Liability. Molecules, 2016, 21, 201. (Impact Factor = 2.4)

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17. Jonathan L. Katz, Takato Hiranita, Theresa A. Kopajtic, Kenner C. Rice, Christophe Mesangeau, Sanju Narayanan, Ahmed H. Abdelazeem, and Christopher R McCurdy. Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists. Journal of Pharmacology and Experimental Therapeutics. April, 2016, doi:10.1124/jpet.116.232728. (Impact Factor = 3.97)

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18. Ahmed H. Abdelazeem, Yasser M.A. Mohamed, Ahmed M. Gouda, Hany A. Omar. Novel Thymohydroquinone-Based Derivatives as Potential Anticancer Agents: Design, Synthesis and Biological Screening. Australlian Journal of Chemistry, 2016, 69, 1277–1284. (Impact Factor = 1.5)

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19. Mostafa H. Abdelrahman, Bahaa G. M. Youssif, Mohamed A abdelgawad, Laurent Treamblu, Ahmed H. Abdelazeem. Synthesis, Biological Evaluation, Docking Study and Ulcerogenicity Profiling of Some Novel Quinoline-2-Carboxamides as Dual COXs/LOX Inhibitors Endowed with Anti-Inflammatory Activity. European Journal of Medicinal Chemistry, 2016. (Accepted) (Impact Factor = 3.5)

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23. Khaled Abdellatif, Mohamed Elsaady, Noha Amin, Ahmed H. Abdelazeem, Ahmed Hefny. Design, synthesis, cyclooxygenase inhibition and anti-inflammatory activity of 3-ethyl-2-pheny-1-substituted-indole derivatives as indomethacin analogs. Bioorganic & Medicinal Chemistry Letters. (SUBMITTED)

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1. McCurdy, C.R.; Mesangeau, C.; Narayanan, S.; Matsumoto, R.R.; Poupaert, J.H.; Avery, B.A.; Abdelazeem, A. H. Highly Selective Sigma Receptor Ligands. US 2010/0329978 A1, Application Number: 12/785, 217, Filed 05/21/2010, US 8,686,008 B2, Apr. 1, 2014.

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2. McCurdy, C.R.; Mesangeau, C.; Avery, B.A.; Abdelazeem, A.H.; Chin, F.T.; Poupaert, J.H. Highly Selective Sigma Receptor Ligands. Application Number: 14/187,035. US 2015/0018339 A1, Jan. 15, 2015.

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